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Does the Ketogenic Diet Support Healthy Aging?

Article ID 06-ND-LI-00297

Bowl of grilled salmon with quinoa, roasted chickpeas, leafy greens, red cabbage, avocado, cucumber and lemon on a wooden table

Can Keto Help You Live Longer?

The ketogenic diet may support certain aspects of metabolic health, but it has not been shown to extend human lifespan or slow biological aging.

Researchers are interested in keto because it changes how the body produces energy and may influence biological processes involved in aging.

Why Is Keto Being Studied for Longevity?

There are 3 main reasons.

1. Ketones May Influence Cellular Aging

During ketosis, the body produces ketones from fat.

Ketones do more than supply energy. Laboratory and animal studies suggest they may influence inflammation, cellular stress and pathways involved in aging.

These findings are scientifically interesting, but their effects on human lifespan remain unknown.

2. Keto Can Reduce Certain Metabolic Risk Factors

Clinical studies show that ketogenic diets can reduce excess body weight, triglycerides and blood sugar in selected populations.

Reducing these risk factors may contribute to healthier aging, particularly in people with metabolic problems.

However, keto can also raise LDL cholesterol, an important cardiovascular risk factor.

3. Animal Studies Have Shown Longevity Benefits

Some experiments in mice have reported longer lifespan or better preservation of physical and cognitive function with ketogenic diets.

Human aging is more complex, and these findings cannot be directly transferred to people.

Is Keto an Anti-Aging Diet?

At present, keto should be viewed as a dietary approach with specific metabolic effects, rather than a proven longevity intervention.

For long-term health, the quality of foods remains important. A diet rich in unsaturated fats, vegetables and adequate protein has a different nutritional profile from one dominated by butter, bacon and processed meat.

The goal is to reduce health risks over time, not simply to maintain ketosis.

Based on Research

Hu FB et al. Diet strategies for promoting healthy aging and longevity: An epidemiological perspective. Journal of Internal Medicine, 2024.

https://onlinelibrary.wiley.com/doi/10.1111/joim.13728

Patikorn C et al. Effects of ketogenic diet on health outcomes: an umbrella review of meta-analyses of randomized clinical trials. BMC Medicine, May 2023.

https://link.springer.com/article/10.1186/s12916-023-02874-y

Author

Monika Mikulicz-Pasler, MD, PhD

Monika Mikulicz-Pasler, MD, PhD

Specialist in Cardiology

Specialist in Internal Medicine

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