Longevity Research Summary
What Is the Gap Between Lifespan and Healthspan?
Research Summary
- Category
- Healthy Aging
- Collection
- Latest
- Evidence Type
- Retrospective Cross-Sectional Global Health Study
- Publication
- JAMA Network Open • December 2024
- Original Publication Title
- Global Healthspan-Lifespan Gaps Among 183 World Health Organization Member States
What Was Studied?
One of the greatest successes of modern medicine is that people are living longer than ever before. However, living longer does not necessarily mean living healthier. This has led longevity researchers to ask an increasingly important question: Are improvements in life expectancy being matched by equivalent gains in years lived in good health?
To answer this question, researchers analysed national health data from 183 World Health Organization (WHO) member states, representing populations across every continent over a period of almost 20 years (2000–2019). The study compared two complementary measures of longevity. Life expectancy estimates how long people are expected to live.
Health-adjusted life expectancy (HALE) estimates how many of those years are expected to be lived in good health by taking into account the impact of chronic diseases, disability and loss of physical or cognitive function. The difference between these two measures is known as the healthspan-lifespan gap. In simple terms, it represents the average number of years people spend living with reduced health after the first signs of disease or disability begin to affect daily life.
The researchers then investigated three key questions: 1. Is the healthspan-lifespan gap becoming wider over time? 2. Does it differ between women and men? 3. Is it associated with the growing burden of chronic noncommunicable diseases?
Understanding this gap is becoming one of the foundations of modern longevity medicine, as it reflects not only how long we live, but how long we remain healthy.
Key Findings
The findings revealed an important paradox of modern healthcare.
Although people are living longer than they did two decades ago, healthy life is not increasing at the same pace. As a result, the average healthspan-lifespan gap has continued to widen and now approaches 10 years worldwide.
In practical terms, this means that many of the years gained through advances in medicine are not necessarily healthy years. Instead, they are often years lived with cardiovascular disease, diabetes, cancer, musculoskeletal disorders, neurological diseases or other chronic conditions that reduce independence and quality of life.
One of the most striking findings concerned sex differences. Women generally live longer than men, yet they also spend an average of 2.4 additional years living with disease or disability. This larger gap was closely associated with a greater burden of noncommunicable diseases - long-term conditions such as cardiovascular disease, diabetes, cancer and chronic respiratory diseases - rather than with longer lifespan alone.
The study also demonstrated that countries carrying a higher burden of chronic diseases tended to have wider healthspan-lifespan gaps. The United States showed the largest gap—12.4 years—highlighting that a long life expectancy does not automatically translate into better population health.
Importantly, the authors caution that a smaller gap is not always a positive finding. In countries where people die younger, the gap may appear shorter simply because many individuals do not survive long enough to experience prolonged periods of disability.
Overall, the findings suggest that extending lifespan alone is no longer a sufficient measure of progress. The next challenge for healthcare is to delay the onset of chronic disease so that more of the years gained are lived in good health rather than with disability.
Why It Matters for Longevity
For many years, healthcare systems measured success primarily by increasing life expectancy. This study suggests that living longer is no longer enough.
It also helps answer one of the most important questions in longevity medicine: Why doesn't living longer always mean living healthier?
The answer lies in the growing healthspan-lifespan gap. Although medical advances have significantly increased life expectancy, they have not delayed the onset of chronic disease to the same extent. As a result, many people are spending more years living with illness, disability and reduced independence rather than enjoying good health.
This concept is closely related to compression of morbidity—one of the fundamental goals of longevity medicine. Compression of morbidity means delaying the onset of chronic disease so that illness occupies a shorter period at the end of life, allowing people to remain healthy, active and independent for longer.
In other words, the success of modern healthcare should be measured not only by adding years to life, but also by adding healthy years to those additional years.
Clinical Perspective
This study reinforces one of the central principles of longevity medicine: preventing disease is more valuable than simply treating it later.
The healthspan-lifespan gap is not an individual prediction. It is a population measure that shows whether societies are extending healthy life or simply prolonging survival with chronic disease.
For clinicians, this shifts the focus toward earlier identification of cardiometabolic risk, preservation of muscle mass and physical function, maintenance of cognitive health, prevention of frailty and optimisation of lifestyle - long before disease becomes clinically apparent.
Earlier prevention, better chronic disease control and sustained attention to physical and cognitive function are therefore essential if additional years of life are to become additional years of health.
Ultimately, the goal of longevity medicine is not simply to help people live longer, but to help them stay healthier for longer.
Key Takeaway
“People worldwide are living longer, but healthy life expectancy is not increasing at the same pace. Living longer is no longer the ultimate goal of medicine. The central challenge of longevity medicine is therefore to narrow the widening gap between lifespan and healthspan. The true measure of success is not simply adding years to life, but ensuring that more of those years are lived in good health, with independence and quality of life.”
Reviewed and Summarized by

Monika Mikulicz-Pasler, MD, PhD
LinkedInSpecialist in Cardiology
Specialist in Internal Medicine
KCM Longevity Clinic
Member of the Polish Society of Longevity Medicine
Original Scientific Publication
- Original Title
- Global Healthspan-Lifespan Gaps Among 183 World Health Organization Member States
- Journal
- JAMA Network Open
- Publication Date
- Authors
- Armin Garmany, Andre Terzic
- Direct Link to the Original Scientific Publication
- https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2827753



